Description Application Action Leaflet Specifications
Enzoimmune Active Immunity Modulator
Enzoimmune Active Immunity Modulator

Enzoimmune Active

Immune Modulator

LIQUID FOOD SUPPLEMENT in the form of a spray or drops. The active substance of the food supplement has been registered for use in the USA with FDA (NDI reg. № 1083). Enzoimunne Active is a registered trade mark of Rosetta Lifecare Bulgaria LTD and is produced under license in Bulgaria (EU) under reg. № 5293/903. This bio-product has shown low toxicity and is well accepted by the body system. Clinical trials show improvements in immunity.

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Description of substances

THE ACTIVE SUBSTANCE is Inactivated pepsin fragment (IPF) derived from pepsin from mucosa (CAS № 9001-75-6) and the method of its extraction and application is patented in the USA as follows: US Patent № 8,309,072 – Irreversible inactivated pepsinogen fragment for modulating immune function. IPF is a complex platform that could be used alone or as a concomitant therapy for a variety of diseases. The substance is made from standardized, purified and lyophilized pepsin containing a polypeptide chain of 327 amino acid residues and one phosphoric acid residue. Using a patented method, a peptide chain of 36 amino acids – (IPF) is isolated, which is involved in a series of immune responses.

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Enzoimmune Active Oral Spray
Enzoimmune Active Oral Spray
Enzoimmune Active Modes of Action
Enzoimmune Active Modes of Action


IPF binds to viral (or other pathogenic) antigens, forming a new antigen complex with them, while blocking their binding to immune cells. An immune response is triggered by modulating the equilibrium between humoral and cellular immune responses by restoring the balance of Th1 and Th2 subunits. IPF also binds to specific tumor antigens, making them recognizable to the immune system. Attached peptide chains to tumor antigens form super antigens that increase the production of antibodies against tumor cells and induce a specific T-lymphocyte response against tumor cells. An increase in CD4 + and an improvement in CD4 + / CD8 + T lymphocyte ratio were observed. Through its mechanism of action, IPF creates non-specific immunity over time.

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For application of EnzoImmune Active Spray/Drops – liquid dietary supplement.

Active Substance:

Inactivated pepsin fragment (IPF), US patent № 8,309,072; USA – FDA reg. № 1083 – 4,5mg / ml.

Additional Ingredients:

Sodium chloride, Sodium acetate, Sodium citrate, Ammonium sulfate, Distilled water.

Recommended Daily Dose:

3 ml – 3 x 8-9 sprays or 3 x 18-20 drops (under the tongue).


Transparent, colorless or slightly yellowish liquid.

Dietary Supplement Form:

50 ml oral spray/drops (under the tongue).


It has a beneficial effect on the immune system, enhancing its ability to fight infections, promoting antibody production and promoting the body’s antioxidant defenses. Helps support liver function and keep cholesterol within normal limits.

Method Of Application And Recommended Dosage:

Adults and children over 14 years of age, to modulate the immune system. The initial stage of absorption begins in the oral cavity after use. The method of administration of the substance is orally, 3 ml per day (3 x 8-9 sprays or 3 x 18-20 drops under the tongue) for three consecutive days per week for 5 weeks. A break of 1 week is recommended, after which the course is repeated 2 more times. Intake of food or liquids for 30 minutes after use is not recommended.


Not established, but hypersensitivity and allergic reactions may occur.

Usage In Pregnancy And Lactation:

Consult with your doctor.

Side Effects:

Not established. Individual intolerance is possible. Does not affect the driving and use of machines.

Special Instructions:

Do not exceed the recommended daily dose. Do not use as a substitute for a varied diet.

Interactions With Other Medicines:

No drug interactions have been reported. As it aids the immune system, EnzoImmune Active Spray/Drops can be combined with anti-inflammatory agents, chemotherapies, antiviral, antibacterial and antimycotic therapies and more. Do not use together with immunosuppressants.

Expiration, Storage And Manufactured:

18 months from production date. Store in dark and cool place at room temperature. Recommended temperature for storage from +4 C to + 10 C. Keep away from children. Manufactured: in EU under license of Zhabilov Trust, USA for Rosetta Lifecare Bulgaria LTD, 8b Bialo Pole Str, 1618 Sofia, Bulgaria, tel: + 359 89 444 03 60, email:


pH of suspension


6.6 – 6.8


pH meter, USP method




4.00 – 8.00 mg / mL of protein


Micro Keldahl method


Bacterial endotoxins


less or equal to 28 EU/mg of IPF


USP 24 <85>Bacterial Endotoxin Test






USP 24 <71>Membrane Filtration


Container closure integrity


Seal and stopper are intact


Visual inspection